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Viral Load as a Factor Affecting the Fatality of Patients Suffering from Severe Fever with Thrombocytopenia Syndrome
- Jo, Heyon-Na;
- Kim, Jieun;
- Hwang, Seong-Yeon;
- Seo, Jun-Won;
- Kim, Da Young;
- 외 18명
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26SCOPUS
26초록
The clinical characteristics and the effect of viral RNA loads on fatality in 56 patients with severe fever with thrombocytopenia syndrome (SFTS) were analyzed. The non-survival group (12 patients) demonstrated a significantly higher mean age (77 years) than the survival group (44 patients, 65 years) (p = 0.003). The survival rates were 91.7% and 8.3% in patients with Ct values ≥30 and differed significantly (p = 0.001) in the survival and non-survival groups, respectively. The survival rates were 52.4% and 47.6% in patients with viral copy numbers ≥10,000 and 94.3% and 5.7% in patients with viral copy numbers <10,000 in the survival and non-survival groups, respectively (p = 0.001). In a multivariate analysis, viral copy numbers and initial Acute Psychologic Assessment and Chronic Health Evaluation II (APACHE II) scores were identified as the factors affecting fatality (p = 0.015 and 0.011, respectively). SFTS viral RNA loads can be useful markers for the clinical prediction of mortality and survival.
키워드
- 제목
- Viral Load as a Factor Affecting the Fatality of Patients Suffering from Severe Fever with Thrombocytopenia Syndrome
- 저자
- Jo, Heyon-Na; Kim, Jieun; Hwang, Seong-Yeon; Seo, Jun-Won; Kim, Da Young; Yun, Na-Ra; Kim, Dong-Min; Kim, Choon-Mee; Jung, Sook In; Kim, Uh Jin; Kim, Seong Eun; Kim, Hyunah; Kim, Eu Suk; Hur, Jian; Kim, Young Keun; Jeong, Hye Won; Heo, Jung Yeon; Jung, Dong Sik; Lee, Hyungdon; Park, Sun Hee; Kwak, Yee Gyung; Lee, Sujin; Lim, Seungjin
- 발행일
- 2022-05
- 유형
- Article
- 저널명
- Viruses
- 권
- 14
- 호
- 5
- 페이지
- 1 ~ 11
- 언어
- ENG
- 출판사
- MDPI
- 발행국가
- 스위스
- 분량
- 11 페이지
- ISSN
- E 1999-4915