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Quantitative analysis of the fate of gold nanocages in vitro and in vivo after uptake by U87-MG tumor cells
- Cho, E.C.;
- Zhang, Y.;
- Cai, X.;
- Moran, C.M.;
- Wang, L.V.;
- 외 1명
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28초록
Not always equal: When a mother cell that contains Au nanocages divides, the nanoparticles are unequally distributed between the two daughter cells. This unequal distribution of nanoparticles as well as their clearance from the cells (see picture) is quantitatively analyzed both in vitro and in vivo using two-photon microscopy and photoacoustic microscopy, respectively.
키워드
biological activity; cell uptake; drug delivery; gold; nanoparticles; Cell uptake; Daughter cells; Gold nanocages; In-vitro; Nanocages; Tumor cells; Two photon microscopy; Bioactivity; Cells; Cytology; Drug delivery; Nanoparticles; Gold; arginyl-glycyl-aspartic acid; arginylglycylaspartic acid; cyclopeptide; drug carrier; gold; metal nanoparticle; oligopeptide; acoustic microscopy; animal; article; brain tumor; cell proliferation; chemistry; human; metabolism; mouse; nude mouse; pathology; time lapse imaging; tumor cell line; xenograft; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Carriers; Gold; Humans; Metal Nanoparticles; Mice; Mice, Nude; Microscopy, Acoustic; Oligopeptides; Peptides, Cyclic; Time-Lapse Imaging; Transplantation, Heterologous
- 제목
- Quantitative analysis of the fate of gold nanocages in vitro and in vivo after uptake by U87-MG tumor cells
- 저자
- Cho, E.C.; Zhang, Y.; Cai, X.; Moran, C.M.; Wang, L.V.; Xia, Y.
- 발행일
- 2013-01
- 유형
- Article
- 권
- 52
- 호
- 4
- 페이지
- 1152 ~ 1155