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초록
Trichomoniasis, a common cause of vaginitis, is the most common sexually transmitted infection in humans, worldwide. It is caused by infection with the single-celled protozoan parasite, Trichomonas vaginalis, which disrupts normal vaginal flora. The administration of metronidazole, approved by the WHO, is currently being used for trichomoniasis treatment. However, there is a great need for development of safe alternative drugs from natural products because of metronidazole's adverse effects. In this investigation, bee venom effectively inhibited Trichomonas vaginalis growth in a concentration-dependent manner. ? 2014 Korean Society of Environmental Risk Assessment and Health Science and Springer Science+Business Media Dordrecht.
키워드
Bee venom; Growth inhibition; Trichomonas vaginalis; apamin; bee venom; glutathione reductase; mast cell degranulating peptide; melittin; metronidazole; phospholipase A2; tinidazole; allergic reaction; antibacterial activity; antifungal activity; article; cell viability; controlled study; cytotoxicity; electron microscopy; liquid chromatography; minimum inhibitory concentration; mutagenicity; nonhuman; pregnancy complication; premature labor; priority journal; sexually transmitted disease; transmission electron microscopy; Trichomonas vaginalis; trichomoniasis
- 제목
- Inhibitory effect of bee venom on the growth of Trichomonas vaginalis
- 저자
- Kim, J.-H.; Ryu, J.-S.; Lee, M.-Y.
- 발행일
- 2014-00
- 유형
- Article
- 권
- 6
- 호
- 1
- 페이지
- 48 ~ 53