Metal-Catalyzed Synthesis of Substituted Indoles

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초록

Indoles are important structural motifs that are commonly found in a diverse array of natural products, pharmaceuticals, and other functional molecules. Consequently, the development of new, more efficient synthetic methods for the construction of substituted indoles continues to be of great importance and considerable interest. Over the past few decades, metal-catalyzed C-C/C-N bond-forming reactions have emerged as a powerful synthetic strategy for heterocyclic synthesis. In this review, we have provided a brief overview of recent advances in the metal-catalyzed synthesis of substituted indoles through the construction of the pyrrole nucleus of indoles, involving the formation of multiple C-C/C-N bonds.

키워드

C-C bond formationC-N bond formationheterocyclesindolestransition metalsC-H ACTIVATIONN BOND FORMATIONONE-POT SYNTHESISNONREARRANGED MONOTERPENOID UNITNITROGEN-CONTAINING HETEROCYCLESHIGHLY FUNCTIONALIZED INDOLESMICROWAVE-ASSISTED SYNTHESISCYCLATIVE CAPTURE APPROACHDIAZO-COMPOUNDS ACCESSEFFICIENT SYNTHESIS
제목
Metal-Catalyzed Synthesis of Substituted Indoles
저자
Youn, So WonKo, Tae Yun
DOI
10.1002/ajoc.201800290
발행일
2018-08
유형
Review
저널명
Asian Journal of Organic Chemistry
7
8
페이지
1467 ~ 1487