Advances in Male Contraception: When Will the Novel Male Contraception be Available?

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4

초록

Many contraceptive methods have been developed over the years due to high demand. However, female contraceptive pills and devices do not work for all females due to health conditions and side effects. Also, the number of males who want to actively participate in family planning is gradually increasing. However, the only contraceptive options currently available to males are condoms and vasectomy. Therefore, many male contraceptive methods, including medication (hormonal and nonhormonal therapy) and mechanical methods, are under development. Reversibility, safety, persistence, degree of invasion, promptness, and the suppression of anti-sperm antibody formation are essential factors in the development of male contraceptive methods. In this paper, male contraceptive methods under development are reviewed according to those essential factors. Furthermore, the timeline for the availability of a new male contraception is discussed.

키워드

Azoospermia; Contraception; Contraceptive agents; Drug development; Spermatogenesis; Sterilization; HORMONAL MALE CONTRACEPTION; SOLUBLE ADENYLYL-CYCLASE; INTRA-VAS DEVICE; RETINOIC ACID; CLINICAL-TRIAL; MAGNETIC-HYPERTHERMIA; ANTISPERM ANTIBODIES; ACROSOME REACTION; CATSPER CHANNELS; SPERM-MOTILITY
제목
Advances in Male Contraception: When Will the Novel Male Contraception be Available?
저자
Kim, Jongwon; So, Byeongchan; Heo, Yongki; So, Hongyun; Jo, Jung Ki
DOI
10.5534/wjmh.230118
발행일
2024-07
유형
Review; Early Access
저널명
The World Journal of Men's Health
권
42
호
3
페이지
487 ~ 501