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A fatal case of hepatitis B virus (HBV) reactivation during long-term, very-low-dose steroid treatment in an inactive HBV carrier.
- Bae, Joong Ho;
- Sohn, Joo Hyun;
- Lee, Hye Soon;
- Park, Hye Sun;
- Hyun, Yil Sik;
- ... Eun, Chang Soo;
- 외 3명
Citations
SCOPUS
20초록
Hepatitis B virus (HBV) may be reactivated after chemotherapy or immunosuppressive therapy, and therefore administration of antiviral agents before such treatment is recommended. Most reported cases of reactivation are associated with high doses of immunosuppressive agents or combination therapy. We present a case of a previously inactive HBV carrier with an acute severe flare-up during a long-term, very-low-dose (2.5 mg/day) steroid treatment for rheumatoid arthritis. We suggest that even a minimal dose of single-regimen oral steroid can cause reactivation of indolent, inactive HBV.
키워드
Hepatitis B virus; Liver failure; Steroids; Virus activation; antivirus agent; hepatitis B surface antigen; immunosuppressive agent; steroid; virus DNA; aged; article; blood; case report; computer assisted tomography; female; genetics; hepatitis B; Hepatitis B virus; human; rheumatoid arthritis; treatment outcome; virus activation; Aged, 80 and over; Antiviral Agents; Arthritis, Rheumatoid; DNA, Viral; Female; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Immunosuppressive Agents; Steroids; Tomography, X-Ray Computed; Treatment Outcome; Virus Activation
- 제목
- A fatal case of hepatitis B virus (HBV) reactivation during long-term, very-low-dose steroid treatment in an inactive HBV carrier.
- 저자
- Bae, Joong Ho; Sohn, Joo Hyun; Lee, Hye Soon; Park, Hye Sun; Hyun, Yil Sik; Kim, Tae Yeob; Eun, Chang Soo; Jeon, Yong Cheol; Han, Dong Soo
- 발행일
- 2012-10
- 유형
- Article
- 권
- 18
- 호
- 2
- 페이지
- 225 ~ 228
- 언어
- ENG
- 출판사
- 대한간학회
- 발행국가
- 대한민국
- 분량
- 4 페이지
- ISSN
- E 2287-285X
P 2287-2728