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A multicenter, retrospective analysis of elderly patients with acute myeloid leukemia who were treated with decitabine
- Yi, Jun Ho;
- Park, Silvia;
- Kim, Jung Han;
- Won, Young-Woong;
- Lim, Do Hyoung;
- ... Uhm, Jieun;
- 외 4명
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10초록
Decitabine is widely accepted as the treatment options for elderly acute myeloid leukemia (AML) patients. However, the efficacy has yet been assessed in Asian population. We retrospectively analyzed the outcomes of 80 Korean elderly AML patients who were treated with decitabine. The median age was 74 years (range, 64 to 86 years) and 6 (7.5%), 48 (60.0%), and 25 (31.3%) patients were categorized to favorable, intermediate, and poor risk group, respectively. The median OS was 10.2 months (95% CI 5.0-15.4). Given that decitabine treatment demonstrated improved clinical outcomes, it could be considered as one of the first-line treatment for Korean elderly AML patients. ? Yi et al.
키워드
Acute myeloid leukemia; Decitabine; Elderly patients; decitabine; acute myeloid leukemia; aged; Article; bacterial infection; cancer patient; clinical outcome; cohort analysis; female; geriatric patient; human; infection; intermediate risk patient; Korean (people); major clinical study; male; multicenter study; multiple cycle treatment; mycosis; overall survival; retrospective study
- 제목
- A multicenter, retrospective analysis of elderly patients with acute myeloid leukemia who were treated with decitabine
- 저자
- Yi, Jun Ho; Park, Silvia; Kim, Jung Han; Won, Young-Woong; Lim, Do Hyoung; Han, Boram; Uhm, Jieun; Kim, Hae Su; Jung, Chul Won; Jang, Jun Ho
- 발행일
- 2018-01
- 유형
- Article
- 저널명
- Oncotarget
- 권
- 9
- 호
- 5
- 페이지
- 6607 ~ 6614
- 언어
- ENG
- 출판사
- Impact Journals
- 발행국가
- 미국
- 분량
- 8 페이지
- ISSN
- P 1949-2553