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Effectiveness of single-pill combination olmesartan/amlodipine/hydrochlorothiazide therapy in patients with apparent resistant hypertension
- Oh, Jaewon;
- Kim, Wonho;
- Kim, Gee-Hee;
- Kim, Hack-Lyoung;
- Park, Sang-Don;
- ... Shin, Jinho;
- 외 5명
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0초록
This pioneering study investigated the real-life effectiveness of single-pill combination (SPC) antihypertensive therapy in patients with uncontrolled blood pressure (BP) and cardiovascular risk factors. After treatment with olmesartan medoxomil/amlodipine besylate/hydrochlorothiazide for 24 weeks, adults with apparent resistant hypertension had significantly reduced systolic BP and approximately 80% achieved target BP. SPC therapy may improve adherence in patients with pseudo-resistant hypertension and is a potentially effective treatment for resistant hypertension.
키워드
Amlodipine; Hydrochlorothiazide; Olmesartan; Amlodipine; Antihypertensive Agents; Drug Combinations; Hydrochlorothiazide; Imidazoles; Olmesartan; Olmesartan Medoxomil; Tetrazoles; Amlodipine; Antihypertensive Agent; Hydrochlorothiazide; Imidazole Derivative; Olmesartan; Tetrazole Derivative; Adult; Aged; Blood Pressure; Combination Drug Therapy; Diagnosis; Drug Combination; Drug Effect; Drug Resistance; Drug Therapy; Female; Human; Hypertension; Male; Middle Aged; Pathophysiology; Treatment Outcome; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Olmesartan Medoxomil; Tetrazoles; Treatment Outcome
- 제목
- Effectiveness of single-pill combination olmesartan/amlodipine/hydrochlorothiazide therapy in patients with apparent resistant hypertension
- 저자
- Oh, Jaewon; Kim, Wonho; Kim, Gee-Hee; Kim, Hack-Lyoung; Park, Sang-Don; Min, Kyung Wan; Hyun, Dongkeun; Hong, Jun Hwa; Lim, Soo; Bae, Ji-Hwan; Shin, Jinho
- 발행일
- 2025-09
- 유형
- Article
- 권
- 39
- 호
- 9
- 페이지
- 675 ~ 678
- 언어
- ENG
- 출판사
- SPRINGERNATURE
- 발행국가
- 영국
- 분량
- 4 페이지
- ISSN
- E 1476-5527
P 0950-9240