Synthesis and Surface Modification of Multi-functional Hybrid Particles

초록

Functionalized organic-inorganic hybrid materials have received great attention due to their potential for scientific and industrial applications.1,2 Among various methods used in the preparation of functionalized hybrid particles, the surface modification of silica particles has been used extensively because of its simplicity.3,4 However, the introduction of multi-functionality on silica particles has not been reported yet. Multi-functional groups in silica particles could endow several interesting features such as selective chemical and physical properties as well as controlled assembly. For example, tri-functional hybrid particles can be used as biological labeling materials with targeting, anchoring, and separation ability depending on the functional groups. In this study, multi-functional organo silica particles were synthesized using a controlled sol-gel process with various silane monomers. Further surface modification of these multifunctional hybrid silica particles could extend the types of functional groups on the silica particles. Di- and tri-functional hybrid particles with thiol, vinyl, amine, methyl, phenyl, epoxy, isocyanate, methyl-methacrylate were prepared and their chemical and physical properties have been investigated. Using self assembly of multi-functional hybrid particles, several interesting structures with controlled array could be produced.