Highly sensitive detection of dipicolinic acid with a water-dispersible terbium-metal organic framework

  • Bhardwaj, Neha
  • Bhardwaj, Sanjeev
  • Mehta, Jyotsana
  • Kim, Ki-Hyun
  • Deep, Akash
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109
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초록

The sensitive detection of dipicolinic acid (DPA) is strongly associated with the sensing of bacterial organisms in food and many types of environmental samples. To date, the demand for a sensitive detection method for bacterial toxicity has increased remarkably. Herein, we investigated the DPA detection potential of a water-dispersible terbium-metal organic framework (Tb-MOF) based on the fluorescence quenching mechanism. The Tb-MOF showed a highly sensitive ability to detect DPA at a limit of detection of 0.04 nM (linear range of detection: 1 nM to 5 mu tM) and also offered enhanced selectivity from other commonly associated organic molecules. The present study provides a basis for the application of Tb-MOF for direct, convenient, highly sensitive, and specific detection of DPA in the actual samples.

키워드

Metal organic frameworkSensorFluorescenceTerbiumDipicolinic acidBACTERIAL-SPORESCOORDINATION MODULATIONNUCLEIC-ACIDCARBON DOTSLUMINESCENCEFABRICATIONADSORPTIONRESISTANCEGRAPHENEEUROPIUM
제목
Highly sensitive detection of dipicolinic acid with a water-dispersible terbium-metal organic framework
저자
Bhardwaj, NehaBhardwaj, SanjeevMehta, JyotsanaKim, Ki-HyunDeep, Akash
DOI
10.1016/j.bios.2016.07.063
발행일
2016-12
유형
Article
저널명
Biosensors and Bioelectronics
86
페이지
799 ~ 804