Graphene bioelectronics

  • Choi, Jonghyun; 
  • Wang, Michael Cai; 
  • Cha, Ronald Young S.; 
  • Park, Won Il; 
  • Nam, SungWoo
Citations

SCOPUS

20

초록

Graphene, a single-atomic-thick planar sheet of sp2-bonded carbon atoms, has been widely investigated for its potential applications in many areas, including biological interfaces, due to its superb electromechanical, optical and chemical properties. In particular, its mechanical flexibility and biocompatibility allow graphene to be configured and utilized as ultra-compliant interfaces for implantable bioelectronics. Furthermore, the superior carrier mobility and transconductance level of graphene field-effect devices lend themselves as high performance/high sensitivity field-effect signal transducers, whose source-drain current is modulated by external field or charge perturbation from chemical and/or biological events. In this article, we review recent developments in graphenebased bioelectronics, focusing on both materials synthesis/fabrication as well as cellular interfaces, and discuss challenges and opportunities for ultra-compliant, highly sensitive, three-dimensional (3D) bioelectronic interfaces in the future.

키워드

Bioelectronics; Cell; Field-Effect Transistor; Flexibility; Graphene; Implantable; Biochemistry; Biocompatibility; Cells; Chemical sensors; Field effect transistors; Interfaces (materials); Surface chemistry; Three dimensional; Bio-electronic interface; Bioelectronics; Biological interface; Charge perturbations; Flexibility; Implantable; Mechanical flexibility; Source-drain current; Graphene; 2 oleoyl 1 palmitoylphosphatidylcholine; adrenalin; carbon nanotube; catecholamine; CD36 antigen; cobalt; copper; dopamine; ethanolamine; folate receptor; folic acid; graphene; nickel; noradrenalin; action potential; atomic force microscopy; biocompatibility; bioenergy; cell growth; electric conductivity; heart muscle cell; human; lipid membrane; metabolic activation; nanofabrication; nonhuman; Raman spectrometry; review; statistical distribution
제목
Graphene bioelectronics
저자
Choi, Jonghyun; Wang, Michael Cai; Cha, Ronald Young S.; Park, Won Il; Nam, SungWoo
DOI
10.1007/s13534-013-0113-z
발행일
2013-12
유형
Review
저널명
Biomedical Engineering Letters (BMEL)
권
3
호
4
페이지
201 ~ 208