상세 보기
초록
Various 2-[6-en-1-ynyl]benzaldehydes and their analogues were successfully cyclized via Huisgen-type [3+2] cycloaddition to the tetracyclic platinum-carbene complex, which would subsequently undergo hydration to afford the tricyclic products in good yields with excellent stereoselectivities. This hydrative cyclization was also applied to the faveline synthesis.
키워드
CONTAINING CARBONYL YLIDES; 5+2 CYCLOADDITION; O-ALKYNYLBENZALDEHYDES; GENERATION; INSERTION; TANDEM; (+/-)-DEOXOFAVELINE; VINYLCYCLOPROPANES; BENZOCYCLOHEPTENES; BENZANNULATION
- 제목
- Pt-Catalyzed Hydrative Cyclization of 2-Enynylbenzaldehydes and Its Application to Faveline Synthesis
- 저자
- Oh, Chang Ho; Lee, Sung Min; Hong, Chang Seop
- 발행일
- 2010-03
- 유형
- Article
- 저널명
- Organic Letters
- 권
- 12
- 호
- 6
- 페이지
- 1308 ~ 1311