상세 보기
Oxidant-Controlled Divergent Syntheses of Pyrazoles and Pyrroles by Copper(I)-Catalyzed Oxidative Coupling of β-Enamino Esters
- Jang, Su San;
- Chang, Jun Yeong;
- Kang, Gil Yeong;
- Youn, So Won
Citations
WEB OF SCIENCE
5Citations
SCOPUS
15초록
Copper(I)-catalyzed oxidative annulations of beta-enamino esters with oxidant dependence are disclosed. These reactions offer divergent syntheses of fully substituted pyrazoles and pyrroles from a common enamine substrate through sequential C-C and N-N or C-N bond-forming reactions in the presence of nitriles as reagent or cosolvent. A mechanism involving radical intermediates generated by single-electron transfer (SET) is proposed for both processes.
키워드
annulation; beta-enamino esters; copper; nitrogen heterocycles; oxidation; FREE-RADICAL REACTIONS; C-C BOND; CONVENIENT SYNTHESIS; DIRECT ACCESS; CYCLIZATION; AMINO; DIMERIZATION; REDUCTION; EFFICIENT; ALKALOIDS
- 제목
- Oxidant-Controlled Divergent Syntheses of Pyrazoles and Pyrroles by Copper(I)-Catalyzed Oxidative Coupling of β-Enamino Esters
- 저자
- Jang, Su San; Chang, Jun Yeong; Kang, Gil Yeong; Youn, So Won
- 발행일
- 2019-09
- 유형
- Article
- 권
- 8
- 호
- 9
- 페이지
- 1668 ~ 1673