Electrospun Nano Composites of Poly(vinyl pyrrolidone)/Nano-silver for Antibacterial Materials

초록

Poly(vinyl pyrrolidone)(PVP) and nano silver are promising candidates for biomedical applications because of their biocompatibility and antibacterial efficacy, respectively. In this research, three kinds of nano silver particles (NSPs) were prepared by the seed mediate growth method and added to electrospinning solutions. PVP/NSPs composites were prepared by electrospinning of 10wt% PVP solutions containing NSPs in ethanol. The electrospinability of PVP/NSPs nano webs in ethanol was investigated according to three different concentrations of NSPs. Electrospun PVP/NSPs nano composites were photocross-linked to improve their water stability. The antibacterial efficacy of PVP/NSPs nano composites were assessed against three types of bacteria; Staphylococcus aureus, Klebsiela pneumoniae and Escherichia coli. Photocross-linked PVP/NSPs nano composites had high water stability and great antibacterial efficacy against all three types of bacteria. Therefore, these composites could be applied as antimicrobial materials.