A label-free single breast cancer cell detection using h-BN sandwiched MoS2 field-effect transistor combined with PDMS-constriction-channel

  • Lee, Jusin; 
  • Yoon, Yousang; 
  • Yang, Heewon; 
  • An, Yoojeong; 
  • Sul, Onejae; 
  • ... Lee, Seung Beck; 
  • 외 1명
Citations

SCOPUS

0

초록

The electrical properties of MoS2 make it highly sensitive to the surface charge density of a cell on MoS2 channel. Here, we fabricated a h-BN sandwiched MoS2 FET integrated with a microfluidic PDMS-constriction-channel for the effective positioning and sensing of cancer cells. By combining advantages of sensitive electrical properties of 2D material and microfluidic geometry, our constriction-channel combined MoS2 sensor could distinguish a single breast cancer cell from the electrolyte by the positive threshold voltage shift of the sensor.

키워드

Cancer cell; Detection; Field-effect transistor; H-BN; Label-free; MDA-MB-231; MoS2; Single cell; Boron nitride; Cytology; Diseases; Electrolytes; Error detection; Field effect transistors; Layered semiconductors; Microchannels; Microfluidics; Molybdenum compounds; Threshold voltage; Cancer cells; H-BN; Label free; MDA-MB-231; MoS2; Single cells; Cells
제목
A label-free single breast cancer cell detection using h-BN sandwiched MoS2 field-effect transistor combined with PDMS-constriction-channel
저자
Lee, Jusin; Yoon, Yousang; Yang, Heewon; An, Yoojeong; Sul, Onejae; Lee, Su Jae; Lee, Seung Beck
발행일
2020-10
유형
Conference Paper
저널명
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
페이지
503 ~ 504