A label-free single breast cancer cell detection using h-BN sandwiched MoS2 field-effect transistor combined with PDMS-constriction-channel

  • Lee, Jusin
  • Yoon, Yousang
  • Yang, Heewon
  • An, Yoojeong
  • Sul, Onejae
  • ... Lee, Seung Beck
  • 외 1명
Citations

SCOPUS

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초록

The electrical properties of MoS2 make it highly sensitive to the surface charge density of a cell on MoS2 channel. Here, we fabricated a h-BN sandwiched MoS2 FET integrated with a microfluidic PDMS-constriction-channel for the effective positioning and sensing of cancer cells. By combining advantages of sensitive electrical properties of 2D material and microfluidic geometry, our constriction-channel combined MoS2 sensor could distinguish a single breast cancer cell from the electrolyte by the positive threshold voltage shift of the sensor.

키워드

Cancer cellDetectionField-effect transistorH-BNLabel-freeMDA-MB-231MoS2Single cellBoron nitrideCytologyDiseasesElectrolytesError detectionField effect transistorsLayered semiconductorsMicrochannelsMicrofluidicsMolybdenum compoundsThreshold voltageCancer cellsH-BNLabel freeMDA-MB-231MoS2Single cellsCells
제목
A label-free single breast cancer cell detection using h-BN sandwiched MoS2 field-effect transistor combined with PDMS-constriction-channel
저자
Lee, JusinYoon, YousangYang, HeewonAn, YoojeongSul, OnejaeLee, Su JaeLee, Seung Beck
발행일
2020-10
유형
Conference Paper
저널명
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
페이지
503 ~ 504