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Total Synthesis of (+/-)-Lycorine from the Endo-Cycloadduct of 3,5-Dibromo-2-pyrone and (E)-beta-Borylstyrene
- Shin, Hyeong-Seob;
- Jung, Yong-Geun;
- Cho, Hyun-Kyu;
- Park, Yong-Gyu;
- Cho, Cheon-Gyu
Citations
WEB OF SCIENCE
49Citations
SCOPUS
51초록
A new synthetic route to (+/-)-lycorine, starting from the endo-cycloadduct of 3,5-dibromo-2-pyrone and (E)-beta-borylstyrene, is reported. Boronate oxidation and a set of reactions including face-selective epoxidation provided the pivotal C1-OH group and C3/C3a double bond.
키워드
DIELS-ALDER REACTION; AMARYLLIDACEAE ALKALOIDS; BIOLOGICAL EVALUATION; LYCORINE DERIVATIVES; (+/-)-CRININE; CONCISE; CASCADE; ROUTE
- 제목
- Total Synthesis of (+/-)-Lycorine from the Endo-Cycloadduct of 3,5-Dibromo-2-pyrone and (E)-beta-Borylstyrene
- 저자
- Shin, Hyeong-Seob; Jung, Yong-Geun; Cho, Hyun-Kyu; Park, Yong-Gyu; Cho, Cheon-Gyu
- 발행일
- 2014-11
- 유형
- Article
- 저널명
- Organic Letters
- 권
- 16
- 호
- 21
- 페이지
- 5718 ~ 5720
- 언어
- ENG
- 출판사
- AMER CHEMICAL SOC
- 발행국가
- 미국
- 분량
- 3 페이지
- ISSN
- E 1523-7052
P 1523-7060