통증 및 부종 관리를 위한 공랭식 중주파 의료기기의 임상적 유효성과 안전성: 후향적 다기관 연구

초록

This study evaluated the clinical efficacy of 'Coollion™', an air-cooled mid-frequency medical device, for managing pain and edema. Coollion is a non-invasive multimodal device that integrates contact-based conductive thermal stimulation (both cooling and heating) with mid-frequency electrical stimulation, utilized in combination with a specialized conductive gel (Coolion gel). A retrospective analysis was conducted on 150 patients with acute or chronic pain and edema at three institutions. Among patients with pain(n = 150), the median VAS pain score significantly decreased from 6.06 before treatment to 2.79 after treatment(p < 0.001). In pateints with edema(n = 98), the median VAS edema score also significantly decreased from 6.92 to 2.50(p < 0.001). Multiple regression analysis revealed that greater treatment responses were associated with higher baseline symptom severity(p < 0.001), and larger reductions were observed when the device was applied to the craniofacial region(p < 0.001). Consistent efficacy was observed across various clinical conditions, including myofascial pain, lower abdominal pain, and post-operative pain and edema following dental implants or extractions. Furthermore, no adverse events or side effects were reported in any of the 150 cases. In conclusion, Coollion therapy presents a promising, safe, and effective non-invasive alternative for the management of pain and edema that can overcome the limitations of conventional pharmacological interventions.

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