Au(I)-catalyzed intramolecular oxidative cyclopropanation of 1,6-enynes derived from propiolamides with diphenyl sulfoxide

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초록

We have developed gold(I)-catalyzed oxidative cyclopropanation of 1,6-enynes derived from propiolamides employing diphenyl sulfoxide as an oxidant. 1,6-Enynes having a terminal alkyne and a propiolamide tether efficiently transformed into cyclopropane carboxaldehyde derivatives.

키워드

IN-SITU GENERATIONINTERMOLECULAR REACTIONSGOLDREARRANGEMENTALKENESYLIDESCYCLOISOMERIZATIONKETONESROUTE
제목
Au(I)-catalyzed intramolecular oxidative cyclopropanation of 1,6-enynes derived from propiolamides with diphenyl sulfoxide
저자
Yeom, Hyun-SukShin, Seunghoon
DOI
10.1039/c2ob27394b
발행일
2013-02
유형
Article
저널명
Organic and Biomolecular Chemistry
11
7
페이지
1089 ~ 1092