Nanomaterials as efficient platforms for sensing DNA

  • Vikrant, Kumar
  • Bhardwaj, Neha
  • Bhardwaj, Sanjeev K.
  • Kim, Ki-Hyun
  • Deep, Akash
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초록

The advent of modern biomedical science has led to various accomplishments such as the early detection of genetic disorders. To pursue further advancement in this field, the development of highly specific, sensitive, and economical probes for DNA may be an emerging imperative. Due to the diverse merits of nanomaterials (e.g., cost-effective, rapid, and precise detection capabilities with improved detection limits), nanomaterial technology has made itself a viable option for designing new and advanced sensors. At present, the techniques for sensing DNA are primarily based upon biosensing approaches. This review article highlights the recent developments in nanotechnology as a potential platform for the detection of DNA. We further identify the present bottlenecks and future scope for the advancement of nanostructure-based DNA sensors and describe the research needs in associated areas.

키워드

NanotechnologyGenosensorsDNABiosensingBiomedicineCancerHYBRIDIZATION CHAIN-REACTIONREDUCED GRAPHENE OXIDEGLASSY-CARBON ELECTRODESLABEL-FREE DETECTIONTARGET RECYCLING AMPLIFICATIONENHANCED RAMAN-SPECTROSCOPYORGANIC FRAMEWORK MIL-101LATERAL FLOW BIOSENSORELECTROCHEMICAL DETECTIONGOLD NANOPARTICLES
제목
Nanomaterials as efficient platforms for sensing DNA
저자
Vikrant, KumarBhardwaj, NehaBhardwaj, Sanjeev K.Kim, Ki-HyunDeep, Akash
DOI
10.1016/j.biomaterials.2019.05.026
발행일
2019-09
유형
Review
저널명
Biomaterials
214
페이지
1 ~ 18