Alginate: Properties and biomedical applications

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초록

Alginate is a biomaterial that has found numerous applications in biomedical science and engineering due to its favorable properties, including biocompatibility and ease of gelation. Alginate hydrogels have been particularly attractive in wound healing, drug delivery, and tissue engineering applications to date, as these gels retain structural similarity to the extracellular matrices in tissues and can be manipulated to play several critical roles. This review will provide a comprehensive overview of general properties of alginate and its hydrogels. their biomedical applications, and suggest new perspectives for future studies with these polymers.

키워드

Biomaterial; Hydrogel; Wound dressing; Drug delivery; Tissue engineering; MESENCHYMAL STEM-CELLS; ENDOTHELIAL GROWTH-FACTOR; MICROSPHERE/HYDROGEL COMBINATION SYSTEM; POLY(ALDEHYDE GULURONATE) HYDROGELS; SYNTHETIC EXTRACELLULAR-MATRIX; PERIPHERAL-NERVE REGENERATION; MOLECULAR-WEIGHT DISTRIBUTION; RGD NANOPATTERNED HYDROGELS; PARTIALLY OXIDIZED ALGINATE; VITRO CONTROLLED-RELEASE
제목
Alginate: Properties and biomedical applications
저자
Lee, Kuen Yong; Mooney, David J.
DOI
10.1016/j.progpolymsci.2011.06.003
발행일
2012-01
유형
Review
저널명
Progress in Polymer Science
권
37
호
1
페이지
106 ~ 126