Aryl Hydrazide beyond as Surrogate of Aryl Hydrazine in the Fischer Indolization: The Synthesis of N-Cbz-indoles, N-Cbz-carbazoles, and N,N '-Bis-Cbz-pyrrolo[2,3-f]indoles

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초록

Aryl hydrazides underwent the Fischer indolization reactions, while the N-carbamate group(s) remained intact to directly provide N-Cbz-indoles. This new method allowed the synthesis of various N-Cbz-carbazoles and N,N'-bis-Cbz-pyrrolo[2,3-f]indoles.

키워드

REARRANGEMENT REACTIONSEFFICIENT SYNTHESISCATALYZED REACTIONSDIRECT OXIDATIONSAZOBENZENESSYSTEMROUTEFUNCTIONALIZATIONREGIOSELECTIVITYHETEROCYCLES
제목
Aryl Hydrazide beyond as Surrogate of Aryl Hydrazine in the Fischer Indolization: The Synthesis of N-Cbz-indoles, N-Cbz-carbazoles, and N,N '-Bis-Cbz-pyrrolo[2,3-f]indoles
저자
Park, In-KeolSuh, Sung-EunLim, Byeong-YunCho, Cheon-Gyu
DOI
10.1021/ol902250x
발행일
2009-12
유형
Article
저널명
Organic Letters
11
23
페이지
5454 ~ 5456