The synthesis of highly functionalized 2-(2-methylenecycloalkyl)pyrroles by palladium-catalyzed cycloreduction

  • Oh, Chang Ho
  • Park, Wooram
  • Kim, Mira
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초록

By utilizing the facile formation of an imine from an aldehyde and an amine, we have discovered a new and highly efficient Pd-catalyzed cycloreduction of enediynals leading to the corresponding 2-(2-methylenecycloalkyl)pyrroles in good to excellent yields.

키워드

palladiumendiynalpyrrolecatalystcycloreductionFURANS2-(1-ALKYNYL)-2-ALKEN-1-ONESCYCLOISOMERIZATIONS
제목
The synthesis of highly functionalized 2-(2-methylenecycloalkyl)pyrroles by palladium-catalyzed cycloreduction
저자
Oh, Chang HoPark, WooramKim, Mira
DOI
10.1055/s-2007-980350
발행일
2007-06
유형
Article
저널명
Synlett
9
페이지
1411 ~ 1415