Acid-Catalyzed [3,3] Sigmatropic Rearrangement of N-Cbz-Diaryl Hydrazide for the Synthesis of Mono-N-Cbz-1,1 '-biaryl-2,2 '-diamine

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초록

N-Cbz-Diaryl hydrazides undergo acid-catalyzed [3,3] sigmatropic rearrangement to afford N-Cbz-1,1'-biaryl-2,2'-diamines. The resultant products can be versatile synthetic platforms for a wide variety of C-2- and/or nonsymmetric axially chiral ligands and organocatalysts.

키워드

Sigmatropic rearrangement; Hydrazides; Cross-coupling; Biaryls; Amines; ASYMMETRIC CATALYSIS; COUPLING REACTIONS; AZOBENZENES; BINOL; ROUTE
제목
Acid-Catalyzed [3,3] Sigmatropic Rearrangement of N-Cbz-Diaryl Hydrazide for the Synthesis of Mono-N-Cbz-1,1 '-biaryl-2,2 '-diamine
저자
Suh, Sung-Eun; Park, In-Keol; Lim, Byeong-Yun; Cho, Cheon-Gyu
DOI
10.1002/ejoc.201001461
발행일
2011-01
유형
Article
저널명
European Journal of Organic Chemistry
권
2011
호
3
페이지
455 ~ 457