Pd-Catalyzed Intramolecular Oxidative C-H Amination: Synthesis of Carbazoles

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210

초록

A Pd-catalyzed oxidative C-H amination of N-Ts-2-arylanilines under ambient temperature using Ozone as an inexpensive, safe, and easy-to-handle oxidant has been developed. This process represents a green and practical method for the facile construction of carbazoles with a broad substrate scope and wide functional group tolerance.

키워드

N BOND FORMATIONTRANSITION-METAL-COMPLEXES1ST TOTAL-SYNTHESISORGANIC-SYNTHESISREDUCTIVE ELIMINATIONCOUPLING REACTIONSDIRECT ARYLATIONBIARYL SYNTHESISPRIMARY AMINESPALLADIUM
제목
Pd-Catalyzed Intramolecular Oxidative C-H Amination: Synthesis of Carbazoles
저자
Youn, So WonBihn, Joon HyungKim, Byung Seok
DOI
10.1021/ol201416u
발행일
2011-07
유형
Article
저널명
Organic Letters
13
14
페이지
3738 ~ 3741