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초록
Pegylated interferon alpha (PEG-IFN-α) is widely used to treat chronic hepatitis C in combination with ribavirin. Many adverse effects of PEG-IFN-α, such as hematologic, psychologic, dermatologic, immunologic, and other abnormalities, have been reported, and some serious adverse events lead to PEG-IFN-α treatment discontinuation. For very rare adverse events such as panniculitis, there are no established guidelines on whether to continue PEG-IFN-α treatment. Published reports on panniculitis induced by PEG-IFN-α 2a are sparse. Herein we report a case of repeated occurrences of panniculitis in a patient with chronic hepatitis C, leading to treatment cessation.
키워드
Adverse effects; Hepatitis C; Panniculitis; Peginterferon alfa-2a; alpha interferon; antivirus agent; macrogol derivative; peginterferon alpha2a; recombinant protein; ribavirin; abdomen; case report; combination drug therapy; diagnostic imaging; echography; female; Hepatitis C, Chronic; human; middle aged; panniculitis; pathology; skin; virology; Abdomen; Antiviral Agents; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Interferon-alpha; Middle Aged; Panniculitis; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Skin; Ultrasonography
- 제목
- Repeated Panniculitis Induced by Pegylated Interferon Alpha 2a in a Patient with Chronic Hepatitis C
- 제목 (타언어)
- 만성 C형간염 환자에서 페그인터페론 알파 2a에 의해 반복적으로 발생한 지방층염
- 저자
- Song, June Seok; Sohn, Joo Hyun; Jeong, Jae Yoon; Min, Ji Hee; Choi, Won Seok; Kim, One Zoong; Pyo, Ju Yeon
- 발행일
- 2016-05
- 유형
- Article
- 저널명
- 대한소화기학회지
- 권
- 67
- 호
- 5
- 페이지
- 272 ~ 276