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초록
A formal synthesis of komaroviquinone has been accomplished by utilizing the Pt-catalyzed hydrative cyclization of an enynal that was easily prepared in a convergent manner. The Pt-catalyzed hydrative cyclization reaction afforded the corresponding tricyclic product, which was utilized in the synthesis of a known precursor that led to the formation of komaroviquinone through an additional four-step synthesis.
키워드
cyclization; enynals; komaroviquinone; natural products; total synthesis; CONTAINING CARBONYL YLIDES; PLATINUM-BOUND PYRYLIUM; DRACOCEPHALUM-KOMAROVI; GENERATION; INSERTION; ALKENES; BOND; CONSTRUCTION; TANDEM
- 제목
- A Formal Synthesis of Komaroviquinone: Use of a Pt-Catalyzed Hydrative Cyclization Reaction
- 저자
- Oh, Chang Ho; Piao, Lanhua; Jung, Jaemun; Kim, Jaewoong
- 발행일
- 2016-10
- 유형
- Article
- 권
- 5
- 호
- 10
- 페이지
- 1237 ~ 1241