Comparative study of the effects of bupropion and escitalopram on Internet gaming disorder

  • Song, Jinuk
  • Park, Jeong Ha
  • Han, Doug Hyun
  • Roh, Sungwon
  • Son, Ji Hyun
  • 외 4명
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초록

Aim: We compared the efficacy of bupropion and escitalopram treatments in Internet gaming disorder (IGD) patients. Methods: We recruited 119 adolescents and adults with IGD. We treated these participants for 6 weeks in three groups as follows: 44 participants were treated with bupropion SR (bupropion group), 42 participants were treated with escitalopram (escitalopram group), and 33 patients without any medication were observed in the community (observation group). At baseline and at the 6-week follow-up visit, all subjects were evaluated using the Clinical Global Impression-Severity Scale, the Young Internet Addiction Scale, the Beck Depression Inventory, the ADHD Rating Scale, and the Behavioral Inhibition and Activation Scales. Results: Both the escitalopram group and the bupropion group showed improvement on all clinical symptom scales after 6 weeks of treatment compared to the observation group. Additionally, the bupropion group showed greater improvement on scores for the Clinical Global Impression-Severity Scale, the Young Internet Addiction Scale, the ADHD Rating Scale, and the Behavioral Inhibition Scale than the escitalopram group. Conclusion: Both bupropion and escitalopram were effective in treating and managing IGD symptoms. Moreover, bupropion appeared to be more effective than escitalopram in improving attention and impulsivity in IGD patients. In addition, attention and impulsivity seem to be important for the management of IGD.

키워드

antidepressantsbupropionescitalopramInternet gaming disorderpharmacotherapyDOUBLE-BLIND DISCONTINUATIONOPEN-LABEL TRIALSUSTAINED-RELEASEADDICTIONMECHANISMANTIDEPRESSANTHYPERACTIVITYADOLESCENTSIMPULSIVITYREWARD
제목
Comparative study of the effects of bupropion and escitalopram on Internet gaming disorder
저자
Song, JinukPark, Jeong HaHan, Doug HyunRoh, SungwonSon, Ji HyunChoi, Tae YoungLee, HyukKim, Tae HoLee, Young Sik
DOI
10.1111/pcn.12429
발행일
2016-11
유형
Article
저널명
Psychiatry and Clinical Neurosciences
70
11
페이지
527 ~ 535