A case of peritoneal tuberculosis developed after infliximab therapy for refractory RA

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초록

Recently, interferon gamma releasing assay has been recommended to compensate the tuberculin skin test (TST) for screening for latent tuberculosis infection (LTBI). Although it improved the detection of LTBI before treatment with tumor necrosis factor blocker, its application to immune suppressed patients is limited. We report a case of peritoneal tuberculosis (TB) developed in a patient who tested positive for TST and QuantiFERON-TB Gold (QFT-G) before infliximab therapy, to emphasize the importance of monitoring during treatment. A 52-year-old woman presented with abdominal distension. She had been diagnosed with seropositive rheumatoid arthritis six years ago. She had started taking infliximab six months ago. All screening tests for TB were performed and the results of all were negative. At admission, the results of repeated TST and QFT-G tests were positive. Histopathological examination confirmed peritoneal TB. The patient started anti-TB therapy and the symptoms were relieved.

키워드

InfliximabPeritonitisTuberculousadenosine deaminaseC reactive proteinethambutolhydroxychloroquineinfliximabisoniazidmethotrexatepyrazinamiderheumatoid factorrifampicinsalazosulfapyridineabdominal distensionacid fast bacteriumadultarticleascitesascites fluidbiopsycase reportcomputer assisted tomographyerythrocyte sedimentation ratefemalehumanLangerhans celllaparoscopyleukocyte differential countlower abdominal painmiliary tuberculosisparacentesisrheumatoid arthritisthorax radiographytuberculin testtuberculous peritonitis
제목
A case of peritoneal tuberculosis developed after infliximab therapy for refractory RA
저자
Min, Ji-YeonBang, So-YoungMin, Seung-YeonLee, Dae-SungKim, Bo-SangKim, Jeong-EunLee, Eun-SungPyo, Ju-YeonSohn, Jang-Won Kim, Tae-Hyung Lee, Hye-Soon
DOI
10.4046/trd.2012.73.4.234
발행일
2012-10
유형
Article
저널명
Tuberculosis and Respiratory Diseases
73
4
페이지
234 ~ 238

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