Metabolic Effects of Gastrectomy with or Without Omentectomy in Gastric Cancer

초록

Background/Aims: The metabolic effects of gastrectomy and the reduction of visceral adiposity through omentectomy for gastric cancer are unknown. Methodology: We retrospectively reviewed of prospectively collected data of 67 patients over one year who underwent radical gastrectomy with either a complete or partial omentectomy for gastric cancer. The change in Body mass index (BMI), triglyceride, low density lipoprotein, high density lipoprotein, and hematological profile were evaluated. Results: In the group of 67 patients changes were observed after 1 year follow-up for BMI (23.7 +/- 3.1 versus 21.3 +/- 2.5kg/m2; p<0.001), triglyceride (155.2 +/- 136.1 versus 89.7 +/- 41.2mg/dL, p=0.011), low density lipoprotein (107.4 +/- 45.4 versus 95.8 +/- 27.5mg/dL, p=0.020), vitamin B12 (681.4 +/- 297.4 versus 558.1 +/- 338.6pg/mL, p=0.076). High density lipoprotein (41.4 +/- 12.6 versus 52.8 +/- 10.5mg/dL) increased after surgery (p<0.001). There were no changes between the complete and partial omentectomy groups for BMI, albumin, triglyceride, lipoprotein, and hemoglobin. Conclusions: Gastrectomy with or without omentectomy induced a decrease of BMI and improvements in metabolic parameters such as triglyceride, low density lipoprotein, high density lipoprotein. Omentectomy had no significant impact on any measured parameter in this group.

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