The cooperative FeCl3/DDQ system for the regioselective synthesis of 3-arylindoles from beta-monosubstituted 2-alkenylanilines

Jang, Su San; Youn, So Won

doi:10.1039/c6ob00074f

상세 보기

The cooperative FeCl3/DDQ system for the regioselective synthesis of 3-arylindoles from beta-monosubstituted 2-alkenylanilines

Jang, Su San;
Youn, So Won

Citations

WEB OF SCIENCE

34

Citations

SCOPUS

35

초록

A highly regioselective synthesis of 3-arylindoles by using the cooperative FeCl3/DDQ system has been developed. This new protocol represents an attractive route for the synthesis of 3-arylindoles from readily accessible non-indole precursors, beta-arylsubstituted 2-styrylanilines, using an inexpensive catalyst and oxidant. Noteworthy is the unique synergetic and synergistic effect of FeCl3 and DDQ on the 1,2-aryl migratory process.

키워드

C-H AMINATION; 3-SUBSTITUTED INDOLES; ANNULATION; INHIBITORS; PHENOLS; ALKENES; HYDROAMINATION; ACTIVATION; CATALYSIS; ENAMINES

제목: The cooperative FeCl3/DDQ system for the regioselective synthesis of 3-arylindoles from beta-monosubstituted 2-alkenylanilines

저자: Jang, Su San; Youn, So Won

DOI: 10.1039/c6ob00074f

발행일: 2016-02

유형: Article

저널명: Organic and Biomolecular Chemistry

권: 14

호: 7

페이지: 2200 ~ 2204