Study of Antibacterial activity of electrospun Cellulose Acetate nanofibers containing Curcumin

초록

Cellulose acetate is the acetate ester of cellulose, the primary structural component of the cell wall of green plants and is one of the most common biopolymers on earth. Electrospun cellulose acetate mats have been used as affinity membranes, antimicrobial membranes, and drug-delivery membranes. Silver nanoparticles have unique antimicrobial properties and have been used with a number of different polymers. Curcumin is a naturally occurring compound in the curcuma longa plant mostly used as a food item. It has anti-oxidant, anti tumor and anti-inflammatory properties. Previously cellulose acetate has been electrospun with curcumin but they don`t contain antibacterial property. This research focuses on the antibacterial property of the Cellulose acetate / curcumin composite. Silver nanoparticles have been introduced in the cellulose acetate / curcumin composite by direct electrospinning them. The results show that the cellulose acetate / curcumin / silver nanoparticles composite possess antibacterial properties as well as the antioxidant, anti-tumor properties of curcumin. This composite has potential applications in the biomedical field.