Intramolecular Imino Diels-Alder Approach to the Synthesis of the Aspidosperma Alkaloid from 3,5-Dibromo-2-pyrone

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초록

A new synthetic route to the key framework of aspidosperma alkaloid was devised from the cycloadduct of 3-(2-nitrophenyl)-5-bromo-2-pyrone via intramolecular imino Diels-Alder reaction.

키워드

CARBON HOMOLOGATIONEFFICIENT SYNTHESISSCHMIDT REACTIONCYCLOADDITIONSTANDEM(+)-ASPIDOSPERMIDINE(+/-)-CRININESTRATEGY
제목
Intramolecular Imino Diels-Alder Approach to the Synthesis of the Aspidosperma Alkaloid from 3,5-Dibromo-2-pyrone
저자
Tam, Nguyen ThanhJung, Eun-JuCho, Cheon-Gyu
DOI
10.1021/ol100489z
발행일
2010-05
유형
Article
저널명
Organic Letters
12
9
페이지
2012 ~ 2014