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Improved total synthesis of (+/-)-trans-dihydronarciclasine, devised for large-scale preparation
- Cho, Young-Suk;
- Cho, Cheon-Gyu
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26초록
New synthetic route to (+/-)-trans-dihydronarciclasine, more suitable for a large-scale preparation, has been devised with the early stage incorporation of ester functionality for direct assembly of the B-ring lactam.
키워드
cycloaddition reaction; amaryllidaccae; trans-dihydronarciclasine; isocarbostyrils; 3,5-dibromo-2-pyrone; ANTITUMOR ALKALOID (+)-PANCRATISTATIN; BETA-AZIDONATION REACTION; ANTINEOPLASTIC AGENTS; AMARYLLIDACEAE ALKALOIDS; EFFICIENT SYNTHESIS; PANCRATISTATIN; NARCICLASINE; 3,5-DIBROMO-2-PYRONE; CYCLOADDITIONS; LYCORICIDINE
- 제목
- Improved total synthesis of (+/-)-trans-dihydronarciclasine, devised for large-scale preparation
- 저자
- Cho, Young-Suk; Cho, Cheon-Gyu
- 발행일
- 2008-02
- 유형
- Article
- 저널명
- Tetrahedron
- 권
- 64
- 호
- 9
- 페이지
- 2172 ~ 2177
- 언어
- ENG
- 출판사
- PERGAMON-ELSEVIER SCIENCE LTD
- 발행국가
- 영국
- 분량
- 6 페이지
- ISSN
- P 0040-4020