Efficacy of prophylactic central neck dissection in hemithyroidectomy for papillary thyroid carcinoma

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초록

Purpose To evaluate the efficacy of prophylactic central neck dissection (pCND) in hemithyroidectomy for clinically node-negative papillary thyroid carcinoma (PTC). Methods We retrospectively analyzed 299 patients who underwent thyroid lobectomy with or without pCND for unilateral PTC. Of the 299 patients, 245 (81.9%) underwent unilateral pCND along with lobectomy, and 54 (18.1%) patients underwent lobectomy without pCND. Propensity score matching was performed for five covariates to reduce selection bias. Results In the baseline cohort of 299 patients, mean age, extrathyroidal extension, T classification and stage were higher in the cases undergoing pCND than in those not undergoing pCND. After propensity score matching, the significant differences between the two groups seen in the baseline cohort disappeared. Recurrence rates and recurrence-free survival curves did not differ between the 2 matched groups each of 54 patients. Conclusion The value of pCND in hemithyroidectomy for PTC is limited.

키워드

Papillary thyroid carcinomaHemithyroidectomyThyroid lobectomyProphylactic central neck dissectionPropensity score matchingLYMPH-NODE DISSECTIONPROGNOSTIC-SIGNIFICANCEASSOCIATION GUIDELINESMANAGEMENT GUIDELINESSURGICAL-MANAGEMENTMETASTASISCANCERMICROCARCINOMALOBECTOMYSURVIVAL
제목
Efficacy of prophylactic central neck dissection in hemithyroidectomy for papillary thyroid carcinoma
저자
Jin, Seok HyunKim, In-SikJi, Yong BaeSong, Chang MyeonChung, Min SungTae, Kyung
DOI
10.1007/s00405-019-05744-7
발행일
2020-03
유형
Article
저널명
European Archives of Oto-Rhino-Laryngology
277
3
페이지
873 ~ 879