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초록
We report the rearrangement of abietane core with trifluoromethanesulfonic anhydride in pyridine to afford the icetexane core, a key intermediate for total syntheses of the structurally intriguing and biologically active compounds (±)-barbatusol, (±)-rosmaridiphenol, and (±)-pisiferin.
키워드
abietane; barbatusol; diterpenoids; icetexane; pisiferin; ring expansion; rosmaridiphenol; PISIFERIC ACID; ANTIPROLIFERATIVE ACTIVITY; ABSOLUTE-CONFIGURATION; BIOLOGICAL-ACTIVITIES; CHEMICAL-COMPOSITION; FORMAL SYNTHESES; ESSENTIAL OILS; SALVIA; ROOTS; (+/-)-BRUSSONOL
- 제목
- Synthesis of the Icetexane Diterpenoids (±)-Rosmaridiphenol, (±)-Pisiferin, and (±)-Barbatusol from Abietane
- 저자
- Le, Thuy Quynh; Lee, JuHui; Oh, Chang Ho
- 발행일
- 2022-06
- 유형
- Article
- 저널명
- Synlett
- 권
- 33
- 호
- 10
- 페이지
- 983 ~ 987