Causes of Childhood Blindness in the United States using the IRIS® Registry (Intelligent Research in Sight)

Lim, Han Woong; Pershing, Suzann; Moshfeghi, Darius M.; Heo, Hwan; Haque, Md Enamul; Lambert, Scott R.

doi:10.1016/j.ophtha.2023.04.004

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Causes of Childhood Blindness in the United States using the IRIS® Registry (Intelligent Research in Sight)

Lim, Han Woong;
Pershing, Suzann;
Moshfeghi, Darius M.;
Heo, Hwan;
Haque, Md Enamul;
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초록

Purpose: To investigate causes of childhood blindness in the United States using the IRISꠑ Registry (Intelligent Research in Sight). Design: Cross-sectional study. Participants: Patients ꠑ 18 years of age with visual acuity (VA) 20/200 or worse in their better-seeing eye in the IRIS Registry during 2018. Methods: Causes of blindness were classified by anatomic site and specific diagnoses. Main Outcome Measures: Percentages of causes of blindness. Results: Of 81 164 children with 2018 VA data in the IRIS Registry, 961 (1.18%) had VA 20/200 or worse in their better-seeing eye. Leading causes of blindness were retinopathy of prematurity (ROP) in 301 patients (31.3%), nystagmus in 78 patients (8.1%), and cataract in 64 patients (6.7%). The retina was the leading anatomic site (47.7%) followed by optic nerve (11.6%) and lens (10.0%). A total of 52.4% of patients had treatable causes of blindness. Conclusions: This analysis offers a unique cross-sectional view of childhood blindness in the United States using a clinical data registry. More than one-half of blind patients had a treatable cause of blindness. Financial Disclosure(s): Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article. Ophthalmology 2023;130:907-913

키워드

Childhood blindness; IRIS registry; Retinopathy of prematurity; adolescent; adult; albinism; amblyopia; aniridia; aphakia; Article; blindness; cataract; child; childhood disease; chorioretinitis; coloboma; controlled study; cornea disease; cornea dystrophy; cross-sectional study; female; glaucoma; human; keratoconus; Leber congenital amaurosis; lens; lung tuberculosis; major clinical study; male; microphthalmia; nystagmus; optic nerve; optic nerve atrophy; optic nerve hypoplasia; patient registry; preschool child; retina; retina detachment; retina dystrophy; retinitis pigmentosa; retinoblastoma; retrolental fibroplasia; scar; school child; Stargardt disease; United States; uveitis; visual acuity; visual impairment; blindness; cataract; complication; newborn; register; visually impaired person

제목: Causes of Childhood Blindness in the United States using the IRIS® Registry (Intelligent Research in Sight)

저자: Lim, Han Woong; Pershing, Suzann; Moshfeghi, Darius M.; Heo, Hwan; Haque, Md Enamul; Lambert, Scott R.

DOI: 10.1016/j.ophtha.2023.04.004

발행일: 2023-09

유형: Article

저널명: Ophthalmology

권: 130

호: 9

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