Semantic variant primary progressive aphasia with a pathogenic variant p.Asp40Gly in the ANXA11 gene

  • Kim, Eun-Joo
  • Moon, So Young
  • Kim, Hee-Jin
  • Jung, Na-Yeon
  • Lee, Sun Min
  • ... Kim, Young Eun
Citations

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초록

We report a patient with right-predominant semantic variant primary progressive aphsia linked with p.Asp40Gly variant of ANXA11, which is the first description of frontotemporal dementia without clinical and electrophysiological evidences of amyotrophic lateral sclerosis associated with a known pathogenic variant of ANXA11.

키워드

ANXA11amyotrophic lateral sclerosisfrontotemporal dementiasemantic variant primary progressive aphasiaannexinannexin a11fluorodeoxyglucose f 18pasp 40glyunclassified drugagedanamnesisArticlebehavior assessmentbrainbrain atrophycase reportclinical articleclinical featuredaily life activitydisease severityfemalefollow upgene mutationgenetic screeninggenetic variabilityglucose metabolismhumanneuroimagingneuropsychiatric inventoryneuropsychological testpositron emission tomographyprimary progressive aphasiasemantic variant primary progressive aphasiashort term memoryT1 weighted imagingT2 weighted imagingtemporal lobeverbal learningwhole exome sequencingword recognitionamyotrophic lateral sclerosisdiagnostic imagingfrontotemporal dementiageneticsprimary progressive aphasiasemantics
제목
Semantic variant primary progressive aphasia with a pathogenic variant p.Asp40Gly in the ANXA11 gene
저자
Kim, Eun-JooMoon, So YoungKim, Hee-JinJung, Na-YeonLee, Sun MinKim, Young Eun
DOI
10.1111/ene.15455
발행일
2022-10
유형
Article
저널명
European Journal of Neurology
29
10
페이지
3124 ~ 3126